Source:http://linkedlifedata.com/resource/pubmed/id/15267009
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-7-22
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pubmed:abstractText |
Current hemodialysis therapy modalities such as online hemodiafiltration (HDF) attempt to enhance solute removal over a wide molecular weight range through a combination of diffusion and convection. While the effects of variations of treatment modalities and conditions have been studied reasonably well, few studies have examined the efficacy of HDF to remove middle molecules in relation to the dialyzer and membrane characteristics. In this investigation, diverse high-flux dialyzers, covering a wide range of membrane permeabilities, were compared under identical in vivo conditions to assess their ability to eliminate larger uremic retention solutes (using beta2-microglobulin as a surrogate of middle molecules) without simultaneously causing excessive leakage of useful proteins such as albumin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0301-0430
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15267009-Albumins,
pubmed-meshheading:15267009-Cross-Over Studies,
pubmed-meshheading:15267009-Female,
pubmed-meshheading:15267009-Hemodiafiltration,
pubmed-meshheading:15267009-Humans,
pubmed-meshheading:15267009-Kidney Failure, Chronic,
pubmed-meshheading:15267009-Male,
pubmed-meshheading:15267009-Membranes, Artificial,
pubmed-meshheading:15267009-Middle Aged,
pubmed-meshheading:15267009-Prospective Studies,
pubmed-meshheading:15267009-beta 2-Microglobulin
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pubmed:year |
2004
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pubmed:articleTitle |
Dialysis membrane-dependent removal of middle molecules during hemodiafiltration: the beta2-microglobulin/albumin relationship.
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pubmed:affiliation |
BioArtProducts GmbH, Rostock, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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