Source:http://linkedlifedata.com/resource/pubmed/id/15264243
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-7-20
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pubmed:abstractText |
Hepatocyte growth factor scatter factor (HGF/SF) elicits a number of biological activities including invasion and migration through activation of its tyrosine kinase receptor c-Met. Over expression of c-Met has been implicated in prostate cancer development and progression. This study examined the effect of a ribozyme transgene, designed to inhibit human c-Met expression, and its impact on in vitro invasion and migration in prostate cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0270-4137
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
317-24
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15264243-Cell Movement,
pubmed-meshheading:15264243-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15264243-Gene Therapy,
pubmed-meshheading:15264243-Humans,
pubmed-meshheading:15264243-Male,
pubmed-meshheading:15264243-Neoplasm Invasiveness,
pubmed-meshheading:15264243-Prostatic Neoplasms,
pubmed-meshheading:15264243-Proto-Oncogene Proteins c-met,
pubmed-meshheading:15264243-RNA, Catalytic,
pubmed-meshheading:15264243-RNA, Messenger,
pubmed-meshheading:15264243-Transfection,
pubmed-meshheading:15264243-Transgenes,
pubmed-meshheading:15264243-Tumor Cells, Cultured
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pubmed:year |
2004
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pubmed:articleTitle |
Targeting the HGF/SF receptor c-met using a hammerhead ribozyme transgene reduces in vitro invasion and migration in prostate cancer cells.
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pubmed:affiliation |
Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom. DAVIESG11@cf.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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