Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2004-7-16
pubmed:abstractText
Current guidelines recommend that only tonsillopharyngitis due to group A beta-haemolytic streptococcus (GABHS) diagnosed by rapid diagnostic test should be treated with antibiotics. Empirical antibiotic therapy must be based on epidemiological surveillance of resistance of GABHS to antibiotics. The aim of our study was to assess the activity of antimicrobial agents currently recommended for the treatment of GABHS tonsillopharyngitis. Method The activity of penicillin G, amoxicillin, cefaclor, cefpodoxime, cefuroxime, erythromycin, clarithromycin and clindamycin was determined against 93 consecutive GABHS isolates collected in 2002. MIC50 and MIC90 of antibiotics tested were determined by agar dilution method according to CA-SFM guidelines. Macrolide resistance genes (ermA, ermB, mef) were detected by PCR. Genetic diversity of erythromycin-resistant isolates was analysed by pulsotypic method after digestion by SmaI (Finger-printing II, Biorad).
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0755-4982
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
703-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:15257225-Acute Disease, pubmed-meshheading:15257225-Adenoids, pubmed-meshheading:15257225-Bacterial Proteins, pubmed-meshheading:15257225-Colony Count, Microbial, pubmed-meshheading:15257225-DNA, Bacterial, pubmed-meshheading:15257225-DNA Fingerprinting, pubmed-meshheading:15257225-Drug Resistance, Bacterial, pubmed-meshheading:15257225-Electrophoresis, Gel, Pulsed-Field, pubmed-meshheading:15257225-Empirical Research, pubmed-meshheading:15257225-Genetic Variation, pubmed-meshheading:15257225-Humans, pubmed-meshheading:15257225-Membrane Proteins, pubmed-meshheading:15257225-Methyltransferases, pubmed-meshheading:15257225-Microbial Sensitivity Tests, pubmed-meshheading:15257225-Paris, pubmed-meshheading:15257225-Patient Selection, pubmed-meshheading:15257225-Pharyngitis, pubmed-meshheading:15257225-Polymerase Chain Reaction, pubmed-meshheading:15257225-Population Surveillance, pubmed-meshheading:15257225-Practice Guidelines as Topic, pubmed-meshheading:15257225-Prevalence, pubmed-meshheading:15257225-Streptococcal Infections, pubmed-meshheading:15257225-Streptococcus pyogenes, pubmed-meshheading:15257225-Tonsillitis
pubmed:year
2004
pubmed:articleTitle
[Current Streptococcus pyogenes sensitivity responsible for acute tonsillopharyngitis in France].
pubmed:affiliation
Service de microbiologie, Hôpital Robert Debré, Paris. patricia.mariani@rdb.ap-hop-paris.fr
pubmed:publicationType
Journal Article, English Abstract