Source:http://linkedlifedata.com/resource/pubmed/id/15256025
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-7-16
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pubmed:abstractText |
A large number (272) of methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered from Italian hospitals during the early and late 1990s were characterized for multidrug resistance pattern and clonal type using a combination of genotyping methods, including pulsed-field gel electrophoresis (PFGE), spaA typing, multilocus sequence typing (MLST), determination of SCC mec type, and hybridization pattern with Tn 554. The majority of MRSA belonged to four genetic lineages: the pandemic Iberian and Brazilian clones, and two unique clonal types-the "Italian" and "Rome" clones of MRSA. The Italian clone carried the SCC mec type I in the genetic background of ST228, which is a double-locus variant of the sequence type of the multidrug-resistant New York/Japanese clone (ST5). The properties of the Rome clone showed several striking similarities to those of the Archaic clone of MRSA that was dominant among MRSA isolates in the mid-1960s to 1970s, but has not been detected since then in recent global surveillance studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1076-6294
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
106-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15256025-Amino Acid Sequence,
pubmed-meshheading:15256025-Anti-Bacterial Agents,
pubmed-meshheading:15256025-DNA, Bacterial,
pubmed-meshheading:15256025-Drug Resistance, Bacterial,
pubmed-meshheading:15256025-Drug Resistance, Multiple,
pubmed-meshheading:15256025-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:15256025-Geography,
pubmed-meshheading:15256025-Humans,
pubmed-meshheading:15256025-Italy,
pubmed-meshheading:15256025-Methicillin Resistance,
pubmed-meshheading:15256025-Staphylococcus aureus
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pubmed:year |
2004
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pubmed:articleTitle |
Clonal types and multidrug resistance patterns of methicillin-resistant Staphylococcus aureus (MRSA) recovered in Italy during the 1990s.
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pubmed:affiliation |
Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa (ITQB/UNL), Oeiras, Portugal.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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