rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-7-16
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pubmed:abstractText |
Ethnicity is an important variable influencing drug response. Thiopurine S-methyltransferase (TPMT) plays an important role in the metabolism of thiopurine drugs. Previous population studies have identified ethnic variations in both phenotype and genotype of TPMT, but limited information is available within Chinese population that comprises at least 56 ethnic groups. The current study was conducted to compare both phenotype and genotype of TPMT in healthy Han and Yao Chinese children.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-10208641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-10634140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-10751626,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-10764140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-10833476,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-11053256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-11110981,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/15255798-11515842,
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0306-5251
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15255798-Adolescent,
pubmed-meshheading:15255798-Child,
pubmed-meshheading:15255798-China,
pubmed-meshheading:15255798-Erythrocytes,
pubmed-meshheading:15255798-Female,
pubmed-meshheading:15255798-Genotype,
pubmed-meshheading:15255798-Humans,
pubmed-meshheading:15255798-Male,
pubmed-meshheading:15255798-Methyltransferases,
pubmed-meshheading:15255798-Phenotype,
pubmed-meshheading:15255798-Polymerase Chain Reaction,
pubmed-meshheading:15255798-Polymorphism, Restriction Fragment Length
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pubmed:year |
2004
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pubmed:articleTitle |
Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: a comparison of Han and Yao ethnic groups.
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pubmed:affiliation |
Department of Pharmacology, Zhongshan Medical College, Guangzhou 510080, PR China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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