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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-7-16
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pubmed:abstractText |
Hypercholesterolaemia is associated with a loss of endothelium-dependent vasodilation, which may facilitate the occurrence of myocardial ischaemia in patients with coronary artery disease (CAD). The improvement of endothelial dilator function after 4 to 6 weeks of oral lipid-lowering therapy has been documented. Whether this early restoration of endothelial function by statins translates into anti-ischaemic effects is unknown. This study was designed to determine the effect of 4 weeks' treatment with 80 mg atorvastatin daily on exercise-induced ischaemia in patients with stable ischaemic heart disease (IHD) receiving standard anti-anginal drug therapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0001-5385
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pubmed:author |
pubmed-author:Belgian Young Cardiologists' Club,
pubmed-author:CarlierMarcM,
pubmed-author:ClaeysMarc JMJ,
pubmed-author:CoolsFrankF,
pubmed-author:CosynsBernardB,
pubmed-author:De MeesterAntoineA,
pubmed-author:DewitBrigitteB,
pubmed-author:GobinEricE,
pubmed-author:HofferEtienneE,
pubmed-author:MissaultLucL,
pubmed-author:VermeerschPaulP
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-74
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pubmed:dateRevised |
2009-6-11
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pubmed:meshHeading |
pubmed-meshheading:15255458-Aged,
pubmed-meshheading:15255458-Angina Pectoris,
pubmed-meshheading:15255458-Cholesterol, LDL,
pubmed-meshheading:15255458-Disease Progression,
pubmed-meshheading:15255458-Exercise Test,
pubmed-meshheading:15255458-Female,
pubmed-meshheading:15255458-Heptanoic Acids,
pubmed-meshheading:15255458-Humans,
pubmed-meshheading:15255458-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:15255458-Hypercholesterolemia,
pubmed-meshheading:15255458-Male,
pubmed-meshheading:15255458-Myocardial Ischemia,
pubmed-meshheading:15255458-Pyrroles,
pubmed-meshheading:15255458-Time Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Short-term effect of atorvastatin on ischaemic threshold in hypercholesterolaemic patients with stable ischaemic heart disease.
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pubmed:affiliation |
Cardiology, Hospital Brain l'Alleud, Rue Wayez 35, 1420 Brain l'Alleud, Belgium. marc.claeys@ua.ac.be
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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