rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-7-15
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pubmed:abstractText |
New data support the importance of the innate immune response in the resolution or progression of pulmonary fibrosis. The presence of CXC chemokine receptor 3-expressing cells, specifically pulmonary NK cells, is necessary to produce IFN-gamma. This is critical in the polarization of the immune response to injury toward a favorable Th1 response and resolution. In contrast, a Th2 response is associated with progressive fibrosis.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-10201901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-10528036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-10673212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-11790668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-11983918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-14503549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-14525967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-14555549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-14711911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-15254596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-7921471,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-9060447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-9186986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-9466968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-9563754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15254582-9842912
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0021-9738
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15254582-Animals,
pubmed-meshheading:15254582-Cytokines,
pubmed-meshheading:15254582-Humans,
pubmed-meshheading:15254582-Immunity, Innate,
pubmed-meshheading:15254582-Killer Cells, Natural,
pubmed-meshheading:15254582-Mice,
pubmed-meshheading:15254582-Pulmonary Fibrosis,
pubmed-meshheading:15254582-Receptors, CXCR3,
pubmed-meshheading:15254582-Receptors, Chemokine,
pubmed-meshheading:15254582-Th1 Cells,
pubmed-meshheading:15254582-Th2 Cells
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pubmed:year |
2004
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pubmed:articleTitle |
Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis.
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pubmed:affiliation |
Department of Medicine, Division of Pulmonary and Critical Care Medicine, The David Geffen School of Medicine at the University of California, Los Angeles 90095-1786, USA. rstrieter@mednet.ucla.edu
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pubmed:publicationType |
Journal Article,
Comment,
Research Support, U.S. Gov't, P.H.S.
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