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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-10-22
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pubmed:abstractText |
Twenty effusions in sixteen patients with malignant peritoneal and/or pleural effusions were treated with intracavitary injection of lentinan. Lentinan was injected at a dosage of 4 mg/week for 4 weeks. In total, sixteen (80%) of twenty lesions demonstrated clinical responses. Performance status was improved in seven patients. The average survival time in responders was 129 days, while, in non-responders, it was 49 days. Serious toxicities were not observed. NK activity of PBMC significantly decreased after lentinan injection. NK activity of PEC in responders was augmented significantly. Anti-Daudi and lymphokine activated killer activity were also augmented or maintained after lentinan injection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0921-299X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-12
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1524950-Adult,
pubmed-meshheading:1524950-Aged,
pubmed-meshheading:1524950-Aged, 80 and over,
pubmed-meshheading:1524950-Ascites,
pubmed-meshheading:1524950-Cell Survival,
pubmed-meshheading:1524950-Exudates and Transudates,
pubmed-meshheading:1524950-Female,
pubmed-meshheading:1524950-Humans,
pubmed-meshheading:1524950-Killer Cells, Lymphokine-Activated,
pubmed-meshheading:1524950-Lentinan,
pubmed-meshheading:1524950-Lymphocytes,
pubmed-meshheading:1524950-Male,
pubmed-meshheading:1524950-Middle Aged,
pubmed-meshheading:1524950-Neoplasms,
pubmed-meshheading:1524950-Neutrophils,
pubmed-meshheading:1524950-Pleural Effusion
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pubmed:year |
1992
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pubmed:articleTitle |
Immunological analysis and clinical effects of intraabdominal and intrapleural injection of lentinan for malignant ascites and pleural effusion.
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pubmed:affiliation |
Second Department of Surgery, Yamaguchi University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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