Source:http://linkedlifedata.com/resource/pubmed/id/15245785
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-7-12
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pubmed:abstractText |
Various studies have evaluated the possible role of the -1438G/A polymorphism within the 5-HT2A receptor gene in the susceptibility to Eating Disorders (EDs). One hundred and forty-eight ED patients (EDp) and 89 control subjects were interviewed by means of the Eating Disorder Examination (EDE) and analyzed for distribution of the -1438G/A polymorphism. Patients with the AA genotype suffering from Anorexia Nervosa and Bulimia Nervosa showed higher Weight and Shape Concern (P = 0.003 and P = 0.010, respectively) scores and greater overall severity of the ED psychopathology (EDE total score) (P = 0.012). The obtained preliminary data suggest the use of dimensional psychopathological measures in ED genetic studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0304-3940
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pubmed:author |
pubmed-author:BagnoliSilviaS,
pubmed-author:BoldriniMauraM,
pubmed-author:CelliniElenaE,
pubmed-author:NacmiasBenedettaB,
pubmed-author:PlacidiGian FrancoGF,
pubmed-author:RavaldiClaudiaC,
pubmed-author:RiccaValdoV,
pubmed-author:RotellaCarlo MariaCM,
pubmed-author:SorbiSandroS,
pubmed-author:TeddeAndreaA,
pubmed-author:di BernardoMilenaM
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pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
365
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15245785-Adult,
pubmed-meshheading:15245785-Anorexia Nervosa,
pubmed-meshheading:15245785-Bulimia,
pubmed-meshheading:15245785-Case-Control Studies,
pubmed-meshheading:15245785-Female,
pubmed-meshheading:15245785-Humans,
pubmed-meshheading:15245785-Polymorphism, Genetic,
pubmed-meshheading:15245785-Promoter Regions, Genetic,
pubmed-meshheading:15245785-Receptor, Serotonin, 5-HT2A
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pubmed:year |
2004
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pubmed:articleTitle |
Psychopathological traits and 5-HT2A receptor promoter polymorphism (-1438 G/A) in patients suffering from Anorexia Nervosa and Bulimia Nervosa.
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pubmed:affiliation |
Department of Neurological and Psychiatric Sciences, Psychiatry Unit, University of Florence, Viale Morgagni, 85, 50134, Italy. valdo.ricca@unifi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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