Linked Life Data

15242668

Source:http://linkedlifedata.com/resource/pubmed/id/15242668

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-6
pubmed:dateCreated
2004-7-9
pubmed:abstractText
The two major cortices of the brain--the cerebral and cerebellar cortex--are massively connected through intercalated nuclei (pontine, cerebellar and thalamic nuclei). We suggest that the two cortices co-operate by generating precise temporal patterns in the cerebral cortex that are detected in the cerebellar cortex as temporal patterns assembled spatially in the mossy fibers. We will begin by showing that the tidal-wave mechanism works in the cerebellar cortex as a read-out mechanism for such spatio-temporal patterns due to the synchronous activity they generate in the parallel fiber system which drives the Purkinje cells--the output neurons of the cerebellar cortex--to fire action potentials. We will review the anatomy of the mossy fibers and show that within a "beam", or "row" of cerebellar cortex the mossy fibers in principle could embed a vast number of tidal-wave generating sequences. Based on anatomical data we will argue that the cerebellar mossy fiber-granule cell-Purkinje cell system can potentially detect and--through learning--select from an enormous number of spatio-temporal patterns.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0928-4257
pubmed:author
pubmed:issnType
Print
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
591-600
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Detection of sequences in the cerebellar cortex: numerical estimate of the possible number of tidal-wave inducing sequences represented.
pubmed:affiliation
Department of Cognitive Neurology, University of Tübingen, Auf der Morgenstelle 15, 72076 Tübingen, Germany. fahad.sultan@uni-tuebingen.de
pubmed:publicationType
Journal Article, Review