Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2004-7-9
pubmed:abstractText
The 'guaco' lianous herb Mikania laevigata, which is widespread in Southern Brazil, is traditionally used to treat bronchitis, asthma and cough. This work investigates the influence of the extraction method, solvent:drug ratio, ethanol proportion, harvest season (summer or winter) and solvent heating on the physicochemical profile of the extracts (dry weight, density, pH) and the coumarin (1,2-benzopyrone) content determined by LC. Among the results obtained, it is observed that higher ethanol content increases the amount of coumarin in the extract. Leaves harvested in summer also produce an extract with a high coumarin yield. The most efficient method of extraction is percolation, independent of the solvent used.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0939-5075
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-200
pubmed:dateRevised
2009-11-4
pubmed:meshHeading
pubmed:articleTitle
Coumarin content and physicochemical profile of Mikania laevigata extracts.
pubmed:affiliation
Universidade do Vale do Itajaí (UNIVALI), Centro de Ciências da Sadde (CCS), Curso de Farmácia, CP 360, 88303-202, Itajaí, Santa Catarina (SC), Brazil. maique@ccs.univali.br
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't