|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002199,
umls-concept:C0006556,
umls-concept:C0007600,
umls-concept:C0009015,
umls-concept:C0325089,
umls-concept:C0439064,
umls-concept:C0449560,
umls-concept:C0679058,
umls-concept:C1547699,
umls-concept:C2347040,
umls-concept:C2700640
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2004-7-8
|
|
pubmed:abstractText |
Mammalian interferon (IFN)-alpha consists of a 23-amino acid signal peptide and a 166-amino acid mature protein. Feline (Fe) IFN-alpha has an extra unique molecule consisting of a 171-amino acid mature protein with a 5-amino acid insertion. We cloned eight new subtypes of cDNA encoding FeIFN- alpha from a feline epithelial cell line. Among all the FeIFN-alpha subtypes, including six that have previously been reported, the variations were found to be far less than those of IFN-alphas of other animals.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0916-7250
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
66
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
725-8
|
|
pubmed:meshHeading |
pubmed-meshheading:15240952-Amino Acid Sequence,
pubmed-meshheading:15240952-Animals,
pubmed-meshheading:15240952-Cats,
pubmed-meshheading:15240952-Cell Line,
pubmed-meshheading:15240952-Cloning, Molecular,
pubmed-meshheading:15240952-DNA, Complementary,
pubmed-meshheading:15240952-DNA Primers,
pubmed-meshheading:15240952-Epithelial Cells,
pubmed-meshheading:15240952-Interferon-alpha,
pubmed-meshheading:15240952-Molecular Sequence Data,
pubmed-meshheading:15240952-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15240952-Sequence Homology, Amino Acid
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Cloning of cDNAs encoding multiple subtypes of feline interferon-alpha from the feline epitherial cell line.
|
|
pubmed:affiliation |
Department of Veterinary Microbiology, School of Veterinary Medicine and Animal Sciences, Kitasato University, Japan.
|
|
pubmed:publicationType |
Journal Article
|
