Source:http://linkedlifedata.com/resource/pubmed/id/15240925
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-7-8
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pubmed:abstractText |
Interictal spikes in patients with epilepsy may be detected by either electroencephalography (EEG) (E-spikes) or magnetoencephalography (MEG) (M-spikes), or both MEG and EEG (E/M-spikes). Localization and amplitude were compared between E/M-spikes and M-spikes in 7 adult patients with extratemporal epilepsy to evaluate the clinical significance of MEG spikes. MEG and EEG were simultaneously measured using a helmet-shaped MEG system with planar-type gradiometers and scalp electrodes of the international 10-20 system. Sources of E/M-spikes and M-spikes were estimated by an equivalent current dipole (ECD) model for MEG at peak latency. Each subject showed 9 to 20 (mean 13.4) E/M-spikes and 9 to 31 (mean 16.3) M-spikes. No subjects showed significant differences in the ECD locations between E/M- and M-spikes. ECD moments of the E/M-spikes were significantly larger in 2 patients and not significantly different in the other 5 patients. The similar localizations of E/M-spikes and M-spikes suggest that combination of MEG and EEG is useful to detect more interictal spikes in patients with extratemporal epilepsy. The smaller tendency of ECD amplitude of the M-spikes than E/M-spikes suggests that scalp EEG may overlook small tangential spikes due to background brain noise. Localization value of M-spikes is clinically equivalent to that of E/M-spikes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0040-8727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
203
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15240925-Adolescent,
pubmed-meshheading:15240925-Adult,
pubmed-meshheading:15240925-Brain,
pubmed-meshheading:15240925-Electroencephalography,
pubmed-meshheading:15240925-Epilepsy,
pubmed-meshheading:15240925-Female,
pubmed-meshheading:15240925-Humans,
pubmed-meshheading:15240925-Magnetoencephalography,
pubmed-meshheading:15240925-Male,
pubmed-meshheading:15240925-Middle Aged,
pubmed-meshheading:15240925-Reproducibility of Results,
pubmed-meshheading:15240925-Sensitivity and Specificity,
pubmed-meshheading:15240925-Time Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Comparison of magnetoencephalographic spikes with and without concurrent electroencephalographic spikes in extratemporal epilepsy.
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pubmed:affiliation |
Department of Neurology, Gil Medical Center, Gachon Medical School, Inchon, Korea.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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