Source:http://linkedlifedata.com/resource/pubmed/id/15237251
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-7-26
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pubmed:abstractText |
A multiple sclerosis (MS)-like illness has been reported in human immunodeficiency virus (HIV)-infected patients, usually in the early stages of HIV infection. We report 3 patients with advanced HIV infection (CD4 lymphocyte count under 200/mm(3)) presenting with monophasic focal leukoencephalopathy, in whom biopsy demonstrated demyelinating lesions compatible with acute MS lesions. In 1 patient, recently started on highly active antiretroviral therapy, MS-like disease could represent an immune reconstitution syndrome. The lesions were reversible in 2 patients, but rapidly fatal in the third patient. These cases show that an MS-like disease may present in advanced HIV infection as focal monophasic leukoencephalopathy with either a reversible or fulminating course, mimicking progressive multifocal leukoencephalopathy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-3022
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15237251-Adult,
pubmed-meshheading:15237251-Demyelinating Diseases,
pubmed-meshheading:15237251-HIV Infections,
pubmed-meshheading:15237251-Humans,
pubmed-meshheading:15237251-Leukoencephalopathy, Progressive Multifocal,
pubmed-meshheading:15237251-Magnetic Resonance Imaging,
pubmed-meshheading:15237251-Male,
pubmed-meshheading:15237251-Middle Aged,
pubmed-meshheading:15237251-Staining and Labeling
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pubmed:year |
2004
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pubmed:articleTitle |
Focal monophasic demyelinating leukoencephalopathy in advanced HIV infection.
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pubmed:affiliation |
Servicio de Neurología, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Carretera de Colmenar km. 9,1, ES-28034 Madrid, Spain. icorral.hrc@salud.madrid.org
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pubmed:publicationType |
Journal Article,
Comparative Study
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