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pubmed-article:15235901pubmed:abstractTextFebrile neutropenia (FN) remains a major dose-limiting complication among patients treated with chemotherapy. Haematopoietic colony stimulating factors (G-CSF and GM-CSF) made possible a significant improvement in the management of FN, both in the therapeutic and in the prophylactic approach. The use of antibiotic prophylaxis also permits a definite reduction of severe infections during neutropenia. Nevertheless, the possible role of these two interventions for secondary prevention of FN is still unclear.lld:pubmed
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pubmed-article:15235901pubmed:articleTitleA prospective randomised evaluation of G-CSF or G-CSF plus oral antibiotics in chemotherapy-treated patients at high risk of developing febrile neutropenia.lld:pubmed
pubmed-article:15235901pubmed:affiliationDepartment of Médecine Interne and Laboratoire d'Investigations Cliniques, H-J Tagnon, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Rue Héger Bordet 1, 1000 Brussels, Belgium. yassine.lalami@bordet.belld:pubmed
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