|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2004-7-5
|
|
pubmed:abstractText |
The role of tumor hypoxia has become a major focus in cancer research since it influences both local and systemic tumor growth. Oxygen measurements taken in human pancreatic cancer have shown extremely low oxygen tension. The aim of this study was to develop an orthotopic model for pancreatic cancer that mimics the specific tumor microenvironment and to evaluate the role of tumor oxygenation in local tumor growth and systemic dissemination in this model.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0022-4804
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
120
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
295-303
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15234226-Abdominal Neoplasms,
pubmed-meshheading:15234226-Animals,
pubmed-meshheading:15234226-Cell Hypoxia,
pubmed-meshheading:15234226-Cell Line, Tumor,
pubmed-meshheading:15234226-Disease Progression,
pubmed-meshheading:15234226-Humans,
pubmed-meshheading:15234226-Lung Neoplasms,
pubmed-meshheading:15234226-Male,
pubmed-meshheading:15234226-Mice,
pubmed-meshheading:15234226-Mice, Nude,
pubmed-meshheading:15234226-Neoplasm Invasiveness,
pubmed-meshheading:15234226-Nitroimidazoles,
pubmed-meshheading:15234226-Oxygen,
pubmed-meshheading:15234226-Pancreatic Neoplasms,
pubmed-meshheading:15234226-Partial Pressure,
pubmed-meshheading:15234226-Staining and Labeling
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model.
|
|
pubmed:affiliation |
Department of Surgery, The David Geffen School of Medicine at UCLA, University of California-Los Angeles, Los Angeles, California, USA. peter.buechler@med.uni-heidelberg.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
