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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
2004-8-4
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pubmed:abstractText |
Inflammation and fibrosis are pathological mechanisms that are partially regulated by cell signalling through the p38 mitogen-activated protein kinase (MAPK) pathway. Elements of the diabetic milieu such as high glucose and advanced glycation end-products induce activation of this pathway in renal cells. Therefore, we examined whether p38 MAPK signalling is associated with the development of human and experimental diabetic nephropathy.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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|
pubmed:issn |
0012-186X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1210-22
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15232685-Animals,
pubmed-meshheading:15232685-Creatinine,
pubmed-meshheading:15232685-Diabetes Mellitus, Experimental,
pubmed-meshheading:15232685-Diabetes Mellitus, Type 2,
pubmed-meshheading:15232685-Diabetic Nephropathies,
pubmed-meshheading:15232685-Hemoglobin A, Glycosylated,
pubmed-meshheading:15232685-Humans,
pubmed-meshheading:15232685-Mice,
pubmed-meshheading:15232685-Mice, Inbred C57BL,
pubmed-meshheading:15232685-Middle Aged,
pubmed-meshheading:15232685-Reference Values,
pubmed-meshheading:15232685-Signal Transduction,
pubmed-meshheading:15232685-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2004
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|
pubmed:articleTitle |
Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy.
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pubmed:affiliation |
Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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