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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2004-7-14
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pubmed:abstractText |
North central China has some of the highest rates of esophageal squamous cell carcinoma in the world with cumulative mortality surpassing 20%. Mitochondrial DNA (mtDNA) accumulates more mutations than nuclear DNA and because of its high abundance has been proposed as a early detection device for subjects with cancer at various sites. We wished to examine the prevalence of mtDNA mutation and polymorphism in subjects from this high risk area of China.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10448277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10486590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10508508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10658535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10720328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-10968778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11058618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11291064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11344040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11381261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11507041,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11516716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11550281,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11585726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11606403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11714113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11861366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-11960540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-12000737,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-12032845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-14639607,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-1468848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-1835609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-3914622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-7960367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15230979-9806551
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
30
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15230979-Carcinoma, Squamous Cell,
pubmed-meshheading:15230979-China,
pubmed-meshheading:15230979-Chromosome Deletion,
pubmed-meshheading:15230979-Complementarity Determining Regions,
pubmed-meshheading:15230979-DNA, Mitochondrial,
pubmed-meshheading:15230979-DNA, Neoplasm,
pubmed-meshheading:15230979-Esophageal Neoplasms,
pubmed-meshheading:15230979-Humans,
pubmed-meshheading:15230979-Incidence,
pubmed-meshheading:15230979-Locus Control Region,
pubmed-meshheading:15230979-Multigene Family,
pubmed-meshheading:15230979-Mutation,
pubmed-meshheading:15230979-Point Mutation,
pubmed-meshheading:15230979-Polymorphism, Genetic,
pubmed-meshheading:15230979-Reference Values,
pubmed-meshheading:15230979-Survival Rate
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pubmed:year |
2004
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pubmed:articleTitle |
Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma.
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pubmed:affiliation |
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. abnetc@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Comparative Study
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