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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-7-1
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pubmed:abstractText |
Behçet's disease (BD) with uveoretinitis is a chronic refractory disease accompanied by ocular attacks. As the decrease in visual acuity due to ocular attack is seriously life-threatening, development of a new drug is anticipated. Since tumor necrosis factor-a (TNF-a) is involved in the symptoms of BD, particularly the activity of ocular symptoms, suppression of TNF-a might be effective in treating BD with uveoretinitis. We conducted a clinical trial of infliximab, an anti-TNF-a chimeric monoclonal antibody, in patients with BD.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0315-162X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1362-8
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pubmed:dateRevised |
2005-9-19
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pubmed:meshHeading |
pubmed-meshheading:15229958-Adolescent,
pubmed-meshheading:15229958-Adult,
pubmed-meshheading:15229958-Antibodies, Monoclonal,
pubmed-meshheading:15229958-Antirheumatic Agents,
pubmed-meshheading:15229958-Behcet Syndrome,
pubmed-meshheading:15229958-Dose-Response Relationship, Drug,
pubmed-meshheading:15229958-Female,
pubmed-meshheading:15229958-Humans,
pubmed-meshheading:15229958-Male,
pubmed-meshheading:15229958-Middle Aged,
pubmed-meshheading:15229958-Retinitis,
pubmed-meshheading:15229958-Treatment Outcome,
pubmed-meshheading:15229958-Tumor Necrosis Factor-alpha,
pubmed-meshheading:15229958-Uveitis
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pubmed:year |
2004
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pubmed:articleTitle |
Efficacy, safety, and pharmacokinetics of multiple administration of infliximab in Behçet's disease with refractory uveoretinitis.
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pubmed:affiliation |
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-Ku, Sapporo 060-8638, Japan.
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pubmed:publicationType |
Journal Article
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