Source:http://linkedlifedata.com/resource/pubmed/id/15227328
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2004-6-30
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| pubmed:abstractText |
Despite the widespread use of K + cardioplegia, the optimal method of intraoperative myocardial preservation remains controversial. Since 1975, in more than 3,500 patients who have undergone myocardial revascularization at our institutions, intraoperative protection has been provided by a technique of cold-blood perfusion without K + cardioplegia. This report describes our technique, analyzes quantitative ultrastructural changes in four patients before and after bypass to assess cellular damage, and details the clinical and angiographic findings in a subgroup of 157 patients followed postoperatively for up to 6 years. In 100 patients in whom multiple vessels were bypassed, vessels were patent on restudy, thereby excluding technical failure as a cause of impaired left ventricular function. Postoperatively, global left ventricular function was unchanged in 80% and improved in 19%, as compared with preoperative function. Left ventricular function deteriorated in only one patient. We conclude that intraoperative oxygenation by cold-blood perfusion is a successful method of myocardial preservation.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
|
| pubmed:month |
Mar
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| pubmed:issn |
0730-2347
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
14
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
39-46; discussion 46
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| pubmed:dateRevised |
2008-11-20
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| pubmed:year |
1987
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| pubmed:articleTitle |
Noncardioplegic myocardial preservation.
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| pubmed:affiliation |
Department of Cardiac Surgery, St. Francis Hospital, Blue Island, Illinois, USA.
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| pubmed:publicationType |
Journal Article
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