Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-6-30
pubmed:abstractText
Actuarial curves and linearized rates of occurrence are statistical functions that traditionally have been used to evaluate freedom from, or incidence of, valve-related events that occur as a result of aortic valve replacement (AVR); however, the instantaneous risk of an event can be more precisely pinpointed by the use of a time-related hazard function. This function was used to analyze 240 cases involving patients who underwent AVR with the Ionescu-Shiley bovine pericardial valve. Follow-up was for 10 years. The period from 60 to 70 months after implantation was apparently critical, since specific and cumulative events (intrinsic tissue failure, thromboembolism, prosthetic valve endocarditis, cumulated events, and death due to valve-related events) peaked during this period. We suspect important degenerative bioprosthetic changes take place during this period and are the cause, in part, for this pattern. In an effort to reduce the incidence of thromboembolism, close observation, and probably antiplatelet drug administration, should be initiated 60 months after implantation of this valve.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
0730-2347
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-4
pubmed:dateRevised
2008-11-20
pubmed:year
1988
pubmed:articleTitle
Instantaneous risk of events following aortic valve replacement with pericardial valves: a ten-year experience.
pubmed:affiliation
Departments of Surgery, Deborah Heart and Lung Center and UMDNJ-Robert Wood Johnson Medical School, Browns Mills, New Jersey, USA.
pubmed:publicationType
Journal Article