Source:http://linkedlifedata.com/resource/pubmed/id/15222685
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-6-29
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pubmed:abstractText |
Several polymorphisms in the insulin receptor substrate-1 (IRS1) gene have been reported in the last years. The most common IRS1 variant, a Gly --> Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations. To determine whether the absence of IRS1 polymorphism is a more general characteristic of Paleo-Indian-derived populations, we examined the Arg972 IRS1 polymorphism in Parakanã Indians and found a lack of this polymorphism in the Parakanã population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0018-7143
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-51
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pubmed:dateRevised |
2011-4-18
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pubmed:meshHeading |
pubmed-meshheading:15222685-Brazil,
pubmed-meshheading:15222685-Consanguinity,
pubmed-meshheading:15222685-Diabetes Mellitus, Type 2,
pubmed-meshheading:15222685-Gene Frequency,
pubmed-meshheading:15222685-Humans,
pubmed-meshheading:15222685-Indians, South American,
pubmed-meshheading:15222685-Insulin Resistance,
pubmed-meshheading:15222685-Leukocytes,
pubmed-meshheading:15222685-Polymerase Chain Reaction,
pubmed-meshheading:15222685-Polymorphism, Genetic,
pubmed-meshheading:15222685-Prevalence,
pubmed-meshheading:15222685-Social Isolation
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pubmed:year |
2004
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pubmed:articleTitle |
Lack of Arg972 polymorphism in the IRS1 gene in Parakanã Brazilian Indians.
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pubmed:affiliation |
Departamento de Clínica Médica, FCM-UNICAMP, Campinas, SP Brazil 13081-970.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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