rdf:type |
|
lifeskim:mentions |
umls-concept:C0002351,
umls-concept:C0007082,
umls-concept:C0009402,
umls-concept:C0030705,
umls-concept:C0036525,
umls-concept:C0038952,
umls-concept:C0060323,
umls-concept:C0175630,
umls-concept:C0242656,
umls-concept:C0430420,
umls-concept:C0441889,
umls-concept:C1522484,
umls-concept:C2698872
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-6-28
|
pubmed:abstractText |
Fibrin formation is required for tumor angiogenesis, metastasis, and invasion. D-dimer, a fibrin degradation product, is produced when crosslinked fibrin is degraded by plasmin. The current study prospectively examined D-dimer levels in patients with metastatic colorectal carcinoma treated in a Phase II randomized trial comparing bevacizumab (Avastin, Genentech, South San Francisco, CA) plus 5-fluorouracil/leucovorin (5-FU/LV) with 5-FU/LV alone.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Carcinoembryonic Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrin Fibrinogen Degradation...,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorouracil,
http://linkedlifedata.com/resource/pubmed/chemical/Leucovorin,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/bevacizumab,
http://linkedlifedata.com/resource/pubmed/chemical/fibrin fragment D
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0008-543X
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2004 American Cancer Society.
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pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
101
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
77-82
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15221991-Adult,
pubmed-meshheading:15221991-Aged,
pubmed-meshheading:15221991-Aged, 80 and over,
pubmed-meshheading:15221991-Antibodies, Monoclonal,
pubmed-meshheading:15221991-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:15221991-Antineoplastic Agents,
pubmed-meshheading:15221991-Carcinoembryonic Antigen,
pubmed-meshheading:15221991-Colorectal Neoplasms,
pubmed-meshheading:15221991-Disease Progression,
pubmed-meshheading:15221991-Female,
pubmed-meshheading:15221991-Fibrin Fibrinogen Degradation Products,
pubmed-meshheading:15221991-Fluorouracil,
pubmed-meshheading:15221991-Humans,
pubmed-meshheading:15221991-Leucovorin,
pubmed-meshheading:15221991-Male,
pubmed-meshheading:15221991-Middle Aged,
pubmed-meshheading:15221991-Tumor Markers, Biological
|
pubmed:year |
2004
|
pubmed:articleTitle |
Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma.
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pubmed:affiliation |
Division of Medical Oncology, Duke University Comprehensive Cancer Center, Durham, NC 27710, USA. black034@mc.duke.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
|