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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-8-4
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pubmed:abstractText |
Dysfunctions of lipoprotein lipase (LPL) have been found to be associated with dyslipidaemias, atherosclerosis, obesity and insulin resistance. There are two conflicting hypotheses regarding the roles of LPL in glucose metabolism and insulin resistance. Whether systemically increased LPL activity would be beneficial or detrimental to insulin sensitivity is yet to be resolved. To address this issue, we studied transgenic rabbits overexpressing human LPL transgene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0012-186X
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pubmed:author |
pubmed-author:FanJJ,
pubmed-author:HigakiYY,
pubmed-author:ItamotoKK,
pubmed-author:KitajimaSS,
pubmed-author:KoikeTT,
pubmed-author:LimMM,
pubmed-author:MambaKK,
pubmed-author:MorimotoMM,
pubmed-author:TauraYY,
pubmed-author:TsutsumiKK,
pubmed-author:WatanabeTT,
pubmed-author:YamadaNN
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1202-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15221136-Adipocytes,
pubmed-meshheading:15221136-Animals,
pubmed-meshheading:15221136-Animals, Genetically Modified,
pubmed-meshheading:15221136-Cholesterol,
pubmed-meshheading:15221136-Dietary Fats,
pubmed-meshheading:15221136-Fatty Acids, Nonesterified,
pubmed-meshheading:15221136-Humans,
pubmed-meshheading:15221136-Insulin,
pubmed-meshheading:15221136-Insulin Resistance,
pubmed-meshheading:15221136-Lipids,
pubmed-meshheading:15221136-Lipoprotein Lipase,
pubmed-meshheading:15221136-Magnetic Resonance Imaging,
pubmed-meshheading:15221136-Rabbits,
pubmed-meshheading:15221136-Triglycerides
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pubmed:year |
2004
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pubmed:articleTitle |
Overexpression of lipoprotein lipase improves insulin resistance induced by a high-fat diet in transgenic rabbits.
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pubmed:affiliation |
Analytical Research Center for Experimental Sciences, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan. kitajims@med.saga-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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