Source:http://linkedlifedata.com/resource/pubmed/id/15219354
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-6-28
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pubmed:abstractText |
This study evaluated whether the common comorbid diagnosis of major depressive disorder (MDD) is associated with an earlier relapse to alcohol use among adolescents with an alcohol use disorder (AUD). The study sample consisted of 116 adolescents between the ages of 14 and 18 with an AUD recruited from treatment facilities in the Pittsburgh area, 50 of whom demonstrated a current MDD. An extensive baseline interview was conducted, followed by monthly interviews of alcohol use conducted by telephone for the following year. Those with current comorbid MDD demonstrated a median survival time of only 19 days until the first drink, while those without MDD demonstrated a median survival time of 45 days, which was a significant difference (Kaplan-Meier survival analysis, Breslow Test Statistic=4.27, df=1, P=.039). These results suggest that the comorbid presence of MDD is associated with an earlier relapse to alcohol use among adolescents with an AUD.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/K01 AA00324,
http://linkedlifedata.com/resource/pubmed/grant/K02 AA00249,
http://linkedlifedata.com/resource/pubmed/grant/K02 AA0291,
http://linkedlifedata.com/resource/pubmed/grant/P50 AA08746,
http://linkedlifedata.com/resource/pubmed/grant/P50 DA05605,
http://linkedlifedata.com/resource/pubmed/grant/R01 AA013370,
http://linkedlifedata.com/resource/pubmed/grant/R01 AA11929,
http://linkedlifedata.com/resource/pubmed/grant/R01 AA13397,
http://linkedlifedata.com/resource/pubmed/grant/R01 DA14635
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0306-4603
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2004 Elsevier Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1035-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15219354-Adolescent,
pubmed-meshheading:15219354-Alcohol-Related Disorders,
pubmed-meshheading:15219354-Alcoholism,
pubmed-meshheading:15219354-Comorbidity,
pubmed-meshheading:15219354-Depressive Disorder,
pubmed-meshheading:15219354-Female,
pubmed-meshheading:15219354-Humans,
pubmed-meshheading:15219354-Interviews as Topic,
pubmed-meshheading:15219354-Male,
pubmed-meshheading:15219354-Recurrence,
pubmed-meshheading:15219354-Substance Abuse Treatment Centers
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pubmed:year |
2004
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pubmed:articleTitle |
Major depression associated with earlier alcohol relapse in treated teens with AUD.
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pubmed:affiliation |
Department of Psychiatry, Western Psychiatric Institute, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA. jcornel@pitt.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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