Source:http://linkedlifedata.com/resource/pubmed/id/15218941
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2004-6-28
|
| pubmed:abstractText |
This study describes the performance of surgically-implanted epimysial stimulating electrodes in the muscles of the lower extremities for use in functional neuromuscular stimulation (FNS) systems for standing after spinal cord injury. A total of 86 epimysial electrodes were implanted in 13 volunteers with low tetraplegia or paraplegia receiving the Case Western Reserve University/Veteran Affairs (CWRU/VA)-implanted standing/transfer neuroprosthesis. The neuroprosthesis consisted of bilateral epimysial electrodes in the knee and hip extensors (vastus lateralis, gluteus maximus, and adductor magnus or semimembranosus) and intramuscular electrodes at the T12/L1 or L1/L2 spinal roots for trunk extension. Recruitment properties, stimulated knee and hip extension moments, standing performance, and mechanical integrity over time were measured for a period up to four years post-implantation. Stimulated thresholds were stable and recruitment was sufficient to generate joint moments adequate for standing, with up to 97% body weight supported by the legs. Four mechanical failures were observed, all in the posterior muscles of the thigh, leaving 95% of all electrodes operational at all followup intervals. Probability of 24-month survival is estimated to be 93% plateauing to a steady state of 90% at four years. These results indicate that epimysial designs are appropriate for long-term clinical use in the large muscles of the lower extremities with implanted motor system neuroprostheses.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
1534-4320
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
279-87
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:15218941-Adult,
pubmed-meshheading:15218941-Electric Stimulation Therapy,
pubmed-meshheading:15218941-Electrodes, Implanted,
pubmed-meshheading:15218941-Equipment Design,
pubmed-meshheading:15218941-Equipment Failure Analysis,
pubmed-meshheading:15218941-Female,
pubmed-meshheading:15218941-Humans,
pubmed-meshheading:15218941-Lower Extremity,
pubmed-meshheading:15218941-Male,
pubmed-meshheading:15218941-Microelectrodes,
pubmed-meshheading:15218941-Middle Aged,
pubmed-meshheading:15218941-Muscle, Skeletal,
pubmed-meshheading:15218941-Muscle Contraction,
pubmed-meshheading:15218941-Paraplegia,
pubmed-meshheading:15218941-Spinal Cord Injuries,
pubmed-meshheading:15218941-Stress, Mechanical,
pubmed-meshheading:15218941-Torque,
pubmed-meshheading:15218941-Treatment Outcome
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Performance of epimysial stimulating electrodes in the lower extremities of individuals with spinal cord injury.
|
| pubmed:affiliation |
Department of Orthopaedics, Cleveland FES Center Technical Development Laboratory, Case Western Reserve University, Cleveland, OH 44106, USA.
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| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|