Source:http://linkedlifedata.com/resource/pubmed/id/15212561
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
2004-6-23
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pubmed:abstractText |
Adapalene (Differin) is a retinoid agent indicated for the topical treatment of acne vulgaris. In clinical trials, 0.1% adapalene gel has proved to be effective in this indication and was as effective as 0.025% tretinoin gel, 0.1% tretinoin microsphere gel, 0.05% tretinoin cream and 0.1% tazarotene gel once every two days; however, the drug was less effective than once-daily 0.1% tazarotene gel. It can be used alone in mild acne or in combination with antimicrobials in inflammatory acne and has proved efficacious as maintenance treatment. Adapalene has a rapid onset of action and a particularly favourable tolerability profile compared with other retinoids. These attributes can potentially promote patient compliance, an important factor in treatment success. Adapalene is, therefore, assured of a role in the first-line treatment of acne vulgaris.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0012-6667
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1465-78
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15212561-Acne Vulgaris,
pubmed-meshheading:15212561-Administration, Cutaneous,
pubmed-meshheading:15212561-Dermatologic Agents,
pubmed-meshheading:15212561-Gels,
pubmed-meshheading:15212561-Humans,
pubmed-meshheading:15212561-Naphthalenes,
pubmed-meshheading:15212561-Randomized Controlled Trials as Topic,
pubmed-meshheading:15212561-Treatment Outcome
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pubmed:year |
2004
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pubmed:articleTitle |
Adapalene: a review of its use in the treatment of acne vulgaris.
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pubmed:affiliation |
Adis International Limited, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, Auckland 1311, New Zealand. demail@adis.cm.nz
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pubmed:publicationType |
Journal Article,
Review
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