rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2004-6-23
|
pubmed:abstractText |
Galactosylated emulsions containing cholesten-5-yloxy-N-(4-((1-imino-2-D-thiogalactosylethyl)amino)butyl)formamide (Gal-C4-Chol) as a "homing device" were developed for hepatocyte-selective drug targeting. The targeting efficiency of galactosylated emulsions was evaluated by a distribution study in mice.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0724-8741
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
932-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15212156-Animals,
pubmed-meshheading:15212156-Carbon Radioisotopes,
pubmed-meshheading:15212156-Chemistry, Physical,
pubmed-meshheading:15212156-Cholesterol,
pubmed-meshheading:15212156-Drug Carriers,
pubmed-meshheading:15212156-Drug Delivery Systems,
pubmed-meshheading:15212156-Egg Yolk,
pubmed-meshheading:15212156-Emulsions,
pubmed-meshheading:15212156-Galactose,
pubmed-meshheading:15212156-Japan,
pubmed-meshheading:15212156-Liposomes,
pubmed-meshheading:15212156-Liver,
pubmed-meshheading:15212156-Mice,
pubmed-meshheading:15212156-Particle Size,
pubmed-meshheading:15212156-Probucol,
pubmed-meshheading:15212156-Solubility,
pubmed-meshheading:15212156-Soybean Oil,
pubmed-meshheading:15212156-Technology, Pharmaceutical,
pubmed-meshheading:15212156-Tissue Distribution,
pubmed-meshheading:15212156-Tritium
|
pubmed:year |
2004
|
pubmed:articleTitle |
Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice.
|
pubmed:affiliation |
Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|