rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-6-22
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pubmed:abstractText |
The invasive potential is increased by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cell lines. We researched whether the signaling pathway activated by GDNF correlates with the nuclear factor-kappaB (NF-kappaB) in human pancreatic cancer cell lines and whether the inhibition of NF-kappaB activity is associated with suppression of invasive potential.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/GDNF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Glial Cell Line-Derived...,
http://linkedlifedata.com/resource/pubmed/chemical/I-kappa B Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Laminin,
http://linkedlifedata.com/resource/pubmed/chemical/Leupeptins,
http://linkedlifedata.com/resource/pubmed/chemical/Luciferases,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappaB inhibitor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/benzyloxycarbonylleucyl-leucyl-leuci...,
http://linkedlifedata.com/resource/pubmed/chemical/matrigel
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1536-4828
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
22-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15211107-Cell Division,
pubmed-meshheading:15211107-Cell Line, Tumor,
pubmed-meshheading:15211107-Collagen,
pubmed-meshheading:15211107-Drug Combinations,
pubmed-meshheading:15211107-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15211107-Genes, Reporter,
pubmed-meshheading:15211107-Glial Cell Line-Derived Neurotrophic Factor,
pubmed-meshheading:15211107-Humans,
pubmed-meshheading:15211107-I-kappa B Proteins,
pubmed-meshheading:15211107-Laminin,
pubmed-meshheading:15211107-Leupeptins,
pubmed-meshheading:15211107-Luciferases,
pubmed-meshheading:15211107-NF-kappa B,
pubmed-meshheading:15211107-Neoplasm Invasiveness,
pubmed-meshheading:15211107-Neoplasm Proteins,
pubmed-meshheading:15211107-Nerve Growth Factors,
pubmed-meshheading:15211107-Pancreatic Neoplasms,
pubmed-meshheading:15211107-Proteoglycans,
pubmed-meshheading:15211107-Recombinant Fusion Proteins,
pubmed-meshheading:15211107-Recombinant Proteins,
pubmed-meshheading:15211107-Signal Transduction,
pubmed-meshheading:15211107-Transcriptional Activation,
pubmed-meshheading:15211107-Transfection
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pubmed:year |
2004
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pubmed:articleTitle |
Glial cell line-derived neurotrophic factor enhances nuclear factor-kappaB activity and invasive potential in human pancreatic cancer cells.
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pubmed:affiliation |
Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. takahasi@med.nagoya-cu.ac.jp
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pubmed:publicationType |
Journal Article
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