Linked Life Data

15205968

Source:http://linkedlifedata.com/resource/pubmed/id/15205968

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-6-18
pubmed:abstractText
Eighteen depressive outpatients were investigated using single-photon emission computerized tomography (SPECT) with a high-affinity dopamine (DA) and serotonin transporter (SERT) specific radioligand, (123)I-labeled beta-CIT (2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane). The patients were tested at the beginning of the study and on follow-up after six months. The severity of depression was evaluated using the 17-item Hamilton Rating Scale of Depression (HRSD). Eight of the eighteen patients had an HRSD score below the median (12 points) on follow-up, and they had a significantly greater increase in (123)I-beta-CIT binding in the midbrain region compared with those patients who did not recover (ANCOVA: F = 8.12; df = 1, 14; p = 0.013). These results indicate that recovery from depression is associated with an increase in (123)I-beta-CIT binding in the midbrain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0940-1334
pubmed:author
pubmed:issnType
Print
pubmed:volume
254
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
152-5
pubmed:dateRevised
2009-5-11
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
123I-beta-CIT binding and recovery from depression. A six-month follow-up study.
pubmed:affiliation
Mental Health Center, Armilankatu 44, 53100 Lappeenranta, Finland. teijamari.laasonen-balk@lappeenranta.fi
pubmed:publicationType
Journal Article, Comparative Study