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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-6-17
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pubmed:abstractText |
Pattern recognition receptors are germ-line encoded receptors that recognize specific pathogen-associated molecules, thereby allowing the innate immune system to distinguish self from nonself structures. Pattern recognition receptors mediate activation of different signaling pathways, resulting in the production of proinflammatory cytokines and the expression of antimicrobial genes. Additionally, pattern recognition receptors play a central role in the activation and direction of the adaptive immune response. This review summarizes recent advances in research trying to elucidate the link between different pattern recognition receptors and inflammatory autoimmune disorders.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/CARD Signaling Adaptor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CARD14 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Guanylate Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NOD1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nod1 Signaling Adaptor Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/TREM1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TYROBP protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1040-8711
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
411-8
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pubmed:dateRevised |
2008-5-7
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pubmed:meshHeading |
pubmed-meshheading:15201605-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:15201605-Arthritis,
pubmed-meshheading:15201605-CARD Signaling Adaptor Proteins,
pubmed-meshheading:15201605-Carrier Proteins,
pubmed-meshheading:15201605-Guanylate Cyclase,
pubmed-meshheading:15201605-Humans,
pubmed-meshheading:15201605-Membrane Glycoproteins,
pubmed-meshheading:15201605-Membrane Proteins,
pubmed-meshheading:15201605-Nod1 Signaling Adaptor Protein,
pubmed-meshheading:15201605-Receptors, Cell Surface,
pubmed-meshheading:15201605-Receptors, Immunologic,
pubmed-meshheading:15201605-Toll-Like Receptors
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pubmed:year |
2004
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pubmed:articleTitle |
Pattern recognition receptors and their involvement in the pathogenesis of arthritis.
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pubmed:affiliation |
Zurich University Children's Hospital, Division for Immunology, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Review
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