Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1992-10-6
|
pubmed:abstractText |
We report a case of Felty's syndrome in which infectious complications due to severe neutropenia could be overcome by short-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, 7 micrograms/kg/day s.c.). Leukocyte counts rose from 1,050/mm3 at presentation to 4,470/mm3 after 15 days of treatment. A flare-up of arthritis was not noted. Defects in granulocyte function and clinical improvement prior to leukocyte rise suggest that the beneficial effect of GM-CSF is mainly due to an improvement of granulocyte function.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-5792
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
190-4
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:1519433-Acute Disease,
pubmed-meshheading:1519433-Aged,
pubmed-meshheading:1519433-Blood Cell Count,
pubmed-meshheading:1519433-Felty's Syndrome,
pubmed-meshheading:1519433-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:1519433-Granulocytes,
pubmed-meshheading:1519433-Humans,
pubmed-meshheading:1519433-Immunoglobulins,
pubmed-meshheading:1519433-Male,
pubmed-meshheading:1519433-Recombinant Proteins
|
pubmed:year |
1992
|
pubmed:articleTitle |
Felty's syndrome: favorable response to granulocyte-macrophage colony-stimulating factor in the acute phase.
|
pubmed:affiliation |
Department of Internal Medicine, Philipps-University, Marburg, FRG.
|
pubmed:publicationType |
Journal Article,
Case Reports
|