Linked Life Data

15193431

Source:http://linkedlifedata.com/resource/pubmed/id/15193431

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2004-6-14
pubmed:abstractText
There are several factors that suggest serotonin [5-hydroxytryptamine (5-HT)] plays a role as a neurotransmitter/neuromodulator within the retina. The presence of mRNAs encoding 5-HT receptors (5-HTR) of the types 5-HT2CR and 5-HT5AR within the rat retina was investigated using in situ hybridization of digoxigenin-labeled probes. The 5HT5AR probe produced no labeling, whereas the 5HT2CR probe hybridized in cells scattered in the inner nuclear and ganglion cell layers. Thus, the 5HT2CR gene is expressed by retinal neurons, some of which represent third-order neurons, either amacrine or ganglion cells. This suggests that 5-HT may modulate the outgoing signal from the retina.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0169-328X
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
140-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Distribution of 5-hydroxytriptamine2C receptor mRNA in rat retina.
pubmed:affiliation
Laboratorio de Neurobiología Molecular y Celular, Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus UNAM-Juriquilla, cp 76 001, AP 1-1141 Querétaro, Mexico. japl_mexico@hotmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't