| pubmed-article:15189782 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0020550 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0015801 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:15189782 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:15189782 | pubmed:issue | 1-3 | lld:pubmed |
| pubmed-article:15189782 | pubmed:dateCreated | 2004-6-10 | lld:pubmed |
| pubmed-article:15189782 | pubmed:abstractText | The effects of acute hyperthyroidism on the vasorelaxing responses to isoprenaline and acetylcholine were investigated in isolated rat renal and femoral arteries. In the renal artery, isoprenaline- and acetylcholine-induced relaxations were significantly greater in hyperthyroid rats than in control rats. In the femoral artery, only the acetylcholine-induced relaxation was significantly greater in hyperthyroid rats than in control rats. In the renal artery, NG-nitro-L-arginine (L-NOARG), an inhibitor of nitric oxide (NO) synthase, reduced isoprenaline- and acetylcholine-induced relaxations in both hyperthyroid and control rats and the isoprenaline-induced relaxation was still greater in hyperthyroid rats than in control rats, but no difference in the acetylcholine-induced relaxation was seen between the two groups of rats since L-NOARG almost abolished the acetylcholine-induced relaxation. In the femoral artery, L-NOAGR reduced the isoprenaline-induced relaxation in control rats but not in hyperthyroid rats, while it almost abolished the acetylcholine-induced relaxation in both groups of rats. 17-Octadecynoic acid (17-ODYA), a cytochrome P-450 monooxygenase inhibitor, reduced the isoprenaline-induced relaxation in renal and femoral arteries from hyperthyroid and control rats, but it did not change the acetylcholine-induced relaxation in both arteries. These results indicate that acute hyperthyroidism significantly enhances beta-adrenoceptor-mediated relaxation of the renal artery and muscarinic receptor-mediated relaxation of both renal and femoral arteries, suggesting that these effects may be due to an alteration in the NO and cytochrome P-450 systems of the artery. | lld:pubmed |
| pubmed-article:15189782 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15189782 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15189782 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15189782 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15189782 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:15189782 | pubmed:author | pubmed-author:HondaHideoH | lld:pubmed |
| pubmed-article:15189782 | pubmed:author | pubmed-author:IwataTakeshiT | lld:pubmed |
| pubmed-article:15189782 | pubmed:copyrightInfo | Copyright 2004 Elsevier B.V. | lld:pubmed |
| pubmed-article:15189782 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15189782 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:15189782 | pubmed:volume | 493 | lld:pubmed |
| pubmed-article:15189782 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15189782 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15189782 | pubmed:pagination | 191-9 | lld:pubmed |
| pubmed-article:15189782 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:meshHeading | pubmed-meshheading:15189782... | lld:pubmed |
| pubmed-article:15189782 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15189782 | pubmed:articleTitle | Acute hyperthyroidism alters adrenoceptor- and muscarinic receptor-mediated responses in isolated rat renal and femoral arteries. | lld:pubmed |
| pubmed-article:15189782 | pubmed:affiliation | Second Department of Physiology, School of Medicine, Showa University, Hatanodai 1-5-8, Shinagawa, Tokyo, 142-8555, Japan. | lld:pubmed |
| pubmed-article:15189782 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15189782 | pubmed:publicationType | Comparative Study | lld:pubmed |
