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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0007785,
umls-concept:C0023516,
umls-concept:C0026882,
umls-concept:C0068355,
umls-concept:C0086418,
umls-concept:C0087086,
umls-concept:C0205245,
umls-concept:C0768581,
umls-concept:C1280500,
umls-concept:C1538631,
umls-concept:C1825005
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pubmed:issue |
1
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pubmed:dateCreated |
2004-6-9
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pubmed:abstractText |
Previous study showed that polymorphism of the NAD(P)H oxidase p22(phox) gene is associated with atherosclerosis, although others could not confirm such association. We investigated the association between p22(phox) C242T polymorphism and thrombotic cerebral infarction and the role of this polymorphism on superoxide-production activity in human neutrophils and promyelocytic HL-60 cells as a model system.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0021-9150
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15186954-Adult,
pubmed-meshheading:15186954-Amino Acid Substitution,
pubmed-meshheading:15186954-Blotting, Northern,
pubmed-meshheading:15186954-Cerebral Infarction,
pubmed-meshheading:15186954-Cytochromes c,
pubmed-meshheading:15186954-Female,
pubmed-meshheading:15186954-Gene Frequency,
pubmed-meshheading:15186954-Genotype,
pubmed-meshheading:15186954-HL-60 Cells,
pubmed-meshheading:15186954-Humans,
pubmed-meshheading:15186954-Immunoblotting,
pubmed-meshheading:15186954-Intracranial Thrombosis,
pubmed-meshheading:15186954-Leukocytes,
pubmed-meshheading:15186954-Male,
pubmed-meshheading:15186954-Membrane Transport Proteins,
pubmed-meshheading:15186954-Middle Aged,
pubmed-meshheading:15186954-Mutation,
pubmed-meshheading:15186954-NADPH Dehydrogenase,
pubmed-meshheading:15186954-NADPH Oxidase,
pubmed-meshheading:15186954-Neutrophils,
pubmed-meshheading:15186954-Phosphoproteins,
pubmed-meshheading:15186954-Polymerase Chain Reaction,
pubmed-meshheading:15186954-Polymorphism, Genetic,
pubmed-meshheading:15186954-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:15186954-Superoxides,
pubmed-meshheading:15186954-Transfection
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pubmed:year |
2004
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pubmed:articleTitle |
Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.
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pubmed:affiliation |
Department of Neurology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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