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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-6-8
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pubmed:abstractText |
The serotonin hypothesis of depression invokes a relative or absolute deficit of serotonin neurotransmission. Reduced synthesis of serotonin in the brain pathways mediating the expression of mood (ie, the limbic cortex) is a plausible candidate mechanism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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|
pubmed:issn |
0003-990X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
556-63
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:15184235-Brain,
pubmed-meshheading:15184235-Carbon Radioisotopes,
pubmed-meshheading:15184235-Caudate Nucleus,
pubmed-meshheading:15184235-Cerebral Cortex,
pubmed-meshheading:15184235-Depressive Disorder,
pubmed-meshheading:15184235-Female,
pubmed-meshheading:15184235-Gyrus Cinguli,
pubmed-meshheading:15184235-Humans,
pubmed-meshheading:15184235-Magnetic Resonance Imaging,
pubmed-meshheading:15184235-Male,
pubmed-meshheading:15184235-Serotonin,
pubmed-meshheading:15184235-Thalamus,
pubmed-meshheading:15184235-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:15184235-Tryptophan
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pubmed:year |
2004
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|
pubmed:articleTitle |
Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression.
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pubmed:affiliation |
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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