Linked Life Data

15181743

Source:http://linkedlifedata.com/resource/pubmed/id/15181743

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2004-6-8
pubmed:abstractText
The purpose of our research was to assess the activity of GSH-Px, GSSG-R, SOD-1 and concentration of GSH, Vit.C and reactive substances with thiobarbituric acid, in brain tumours with Ist, IInd, IIIrd and IVth levels of biological malignancy. The research was conducted in 105 samples obtained from patients undergoing surgery in the Department of Neurosurgery of the Medical University of Bia?ystok between the years 1996-2001. The obtained values of the above enzyme activities and the concentration of the examined substances in brain tumours were compared to the control values determined in 15 samples of histopathology unchanged nerve tissue. THE RESULTS: The increase in all enzymes activities in brain tumours is statistically significant (p < 0.05) as compared to the control level in normal nerve tissue alto a significant decrease (p < 0.05) of the GSH and ascorbate concentration and a significant increase (p < 0.05) in the level of thiobarbituric acid-reactive substances in the examined brain tumours was found in comparison to the concentration of the above substances in normal nerve tissue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0043-5147
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Evaluation of antioxidant enzymes activity and concentration of non-enzymatic antioxidants in human brain tumours.
pubmed:affiliation
Department of Neurosurgery, Medical University of Bia?ystok.
pubmed:publicationType
Journal Article, Comparative Study