|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000726,
umls-concept:C0014834,
umls-concept:C0015505,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026809,
umls-concept:C0040048,
umls-concept:C0205263,
umls-concept:C0243026,
umls-concept:C0333348,
umls-concept:C1516002,
umls-concept:C1704259,
umls-concept:C1705987
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2004-6-7
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|
pubmed:abstractText |
Anticoagulants have gained increasing attention for the treatment of sepsis. Inhibition of the tissue factor (TF)/factor (F) VIIa pathway has been shown to attenuate the activation of coagulation and to prevent death in a primate model of sepsis caused by gram-negative bacteria.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0022-1899
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
189
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2308-17
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pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:15181580-Animals,
pubmed-meshheading:15181580-Blood Coagulation,
pubmed-meshheading:15181580-Disease Models, Animal,
pubmed-meshheading:15181580-Escherichia coli,
pubmed-meshheading:15181580-Escherichia coli Infections,
pubmed-meshheading:15181580-Factor VIIa,
pubmed-meshheading:15181580-Helminth Proteins,
pubmed-meshheading:15181580-Inflammation,
pubmed-meshheading:15181580-Male,
pubmed-meshheading:15181580-Mice,
pubmed-meshheading:15181580-Mice, Inbred C57BL,
pubmed-meshheading:15181580-Peritonitis,
pubmed-meshheading:15181580-Thromboplastin
|
|
pubmed:year |
2004
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|
pubmed:articleTitle |
Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice.
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|
pubmed:affiliation |
Laboratory of Experimental Internal Medicine and Department of Infectious Diseases, Tropical Medicine, and AIDS, University of Amsterdam, The Netherlands. s.weijer@amc.uva.nl.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
