pubmed-article:15181145 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C0178566 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C0599894 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C1521871 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C0205349 | lld:lifeskim |
pubmed-article:15181145 | lifeskim:mentions | umls-concept:C0449445 | lld:lifeskim |
pubmed-article:15181145 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:15181145 | pubmed:dateCreated | 2004-6-7 | lld:pubmed |
pubmed-article:15181145 | pubmed:abstractText | Conventional nuclear medicine imaging with large radiolabeled molecules such as antitumor antibodies suffers from slow localization and clearance. Pretargeting is under active investigation as an alternative using either (strept)avidin/biotin, bispecific antibodies, or oligomers. However, only the use of oligomers such as phosphorodiamidate morpholinos (MORFs) in pretargeting offers the potential of signal amplification at the target. Amplification targeting is a multistep procedure with the potential to greatly improve target localization of radioactivity (and eventually drugs) through the intermediate use of polymers conjugated with multiple copies of oligomers. | lld:pubmed |
pubmed-article:15181145 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15181145 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15181145 | pubmed:language | eng | lld:pubmed |
pubmed-article:15181145 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15181145 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15181145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15181145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:15181145 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15181145 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15181145 | pubmed:month | Jun | lld:pubmed |
pubmed-article:15181145 | pubmed:issn | 0161-5505 | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:LiuGuozhengG | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:RusckowskiMar... | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:HnatowichDona... | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:HeJiangJ | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:GuptaSureshS | lld:pubmed |
pubmed-article:15181145 | pubmed:author | pubmed-author:ZhangYuminY | lld:pubmed |
pubmed-article:15181145 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15181145 | pubmed:volume | 45 | lld:pubmed |
pubmed-article:15181145 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15181145 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15181145 | pubmed:pagination | 1087-95 | lld:pubmed |
pubmed-article:15181145 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:15181145 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:15181145 | pubmed:articleTitle | Amplification targeting: a modified pretargeting approach with potential for signal amplification-proof of a concept. | lld:pubmed |
pubmed-article:15181145 | pubmed:affiliation | Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. | lld:pubmed |
pubmed-article:15181145 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15181145 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:15181145 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:15181145 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
pubmed-article:15181145 | pubmed:publicationType | Validation Studies | lld:pubmed |
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