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pubmed-article:15180766pubmed:abstractTextFcgammaRIIB are low-affinity immunoglobulin (Ig)G receptors that we previously demonstrated to negatively regulate IgE-induced mast cell activation when coaggregated with FcepsilonRI. Here, we engineered and characterized a bispecific reagent capable of coaggregating FcgammaRIIB with FcepsilonRI on human mast cells and basophils.lld:pubmed
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pubmed-article:15180766pubmed:articleTitleA bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils.lld:pubmed
pubmed-article:15180766pubmed:affiliationTanox Inc., Houston, TX, USA.lld:pubmed
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