Source:http://linkedlifedata.com/resource/pubmed/id/15179350
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-6-4
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pubmed:abstractText |
Genetic factors appear to be important in the pathogenesis of cardiovascular and cerebrovascular disease. Adhesion molecules like the members of the selectin family participate in the interaction between leukocytes and the endothelium. They are also involved in the pathogenesis of the atherosclerotic process. In E-selectin, exchange from serine to arginine (position 128, S128R) is correlated with early atherosclerosis. The aim of this study was to assess E-selectin Ser128Arg polymorphism in subjects with clinical and instrumental evidence of atherosclerosis and to analyze the correlations with clinical severity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-9509
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
143-7
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:15179350-Aged,
pubmed-meshheading:15179350-Arginine,
pubmed-meshheading:15179350-Arteriosclerosis,
pubmed-meshheading:15179350-E-Selectin,
pubmed-meshheading:15179350-Female,
pubmed-meshheading:15179350-Humans,
pubmed-meshheading:15179350-Male,
pubmed-meshheading:15179350-Middle Aged,
pubmed-meshheading:15179350-Polymorphism, Genetic,
pubmed-meshheading:15179350-Serine,
pubmed-meshheading:15179350-Severity of Illness Index
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pubmed:year |
2004
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pubmed:articleTitle |
Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease.
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pubmed:affiliation |
General Surgery Unit, Department of Medicine, Surgery and Dentistry, University of Milan, S. Paolo Hospital, Milan, Italy. giorgio.ghilardi@unimi.it
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pubmed:publicationType |
Journal Article
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