Linked Life Data

15173684

Source:http://linkedlifedata.com/resource/pubmed/id/15173684

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-7-23
pubmed:abstractText
The purpose of this paper is to provide a brief review of the current state of our knowledge regarding pesticides and oxidative stress. To this end, we performed a search of the literature using Medline/Index Medicus, EMBASE/Excerpta Medica, and Chemical Abstracts; most of the relevant citations were studied and summarized. In order to better understand the nature of oxidative stress, the principles of free radical production and the body's normal defense system are discussed. The pesticides are categorized and discussed according to their ability to produce lipid peroxidation or alter body antioxidant status. It is concluded that stimulation of free radical production, induction of lipid peroxidation, and disturbance of the total antioxidant capability of the body are mechanisms of toxicity in most pesticides, including organophosphates, bipyridyl herbicides and organochlorines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1234-1010
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
RA141-7
pubmed:dateRevised
2006-11-17
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Pesticides and oxidative stress: a review.
pubmed:affiliation
Department of Toxicology & Pharmacology, Faculty of Pharmacy and Laboratory of Toxicology, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 14155-6451, Iran. mohammad@sina.tums.ac.ir
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't