Apoptosis-related proteins are important molecules for predicting chemotherapy response and prognosis in adult acute myeloid leukemia (AML). However, data on the expression and prognostic impact of these molecules in childhood AML are rare.
High expression levels of x-linked inhibitor of apoptosis protein and survivin correlate with poor overall survival in childhood de novo acute myeloid leukemia.
Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Berlin-Buch, Universitätsmedizin Berlin, Berlin, Germany. ingo.tamm@charite.de
