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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-5-31
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pubmed:abstractText |
CARD15 gene mutations have been demonstrated to confer a high risk of Crohn's disease (CD). Despite this, recent studies reported variable associations between CD and CARD15 mutations in distinct ethnic groups, thus raising the hypothesis that genetic and/or allelic heterogeneity may influence the relationship between CARD15 and CD. The purpose of this study was to evaluate the frequency of the main mutations of the CARD15 gene (Leu 1007fsinsC, Arg702Trp, and Gly908Arg) in Italian CD patients and to establish possible genotype-phenotype correlations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0998
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pubmed:author |
pubmed-author:BianconeLiviaL,
pubmed-author:BlancoGiovanna Del VecchioGdel V,
pubmed-author:BorgianiPaolaP,
pubmed-author:D'ApiceMaria RosariaMR,
pubmed-author:De NigrisFrancescaF,
pubmed-author:MonteleoneGiovanniG,
pubmed-author:MonteleoneIvanI,
pubmed-author:NovelliGiuseppeG,
pubmed-author:PalloneFrancescoF,
pubmed-author:ValloLauraL,
pubmed-author:VavassoriPieroP
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
116-21
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pubmed:dateRevised |
2008-5-13
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pubmed:meshHeading |
pubmed-meshheading:15168811-Adolescent,
pubmed-meshheading:15168811-Adult,
pubmed-meshheading:15168811-Age Distribution,
pubmed-meshheading:15168811-Aged,
pubmed-meshheading:15168811-Carrier Proteins,
pubmed-meshheading:15168811-Case-Control Studies,
pubmed-meshheading:15168811-Confidence Intervals,
pubmed-meshheading:15168811-Crohn Disease,
pubmed-meshheading:15168811-Female,
pubmed-meshheading:15168811-Gene Expression Regulation,
pubmed-meshheading:15168811-Gene Frequency,
pubmed-meshheading:15168811-Genetic Predisposition to Disease,
pubmed-meshheading:15168811-Genetics, Population,
pubmed-meshheading:15168811-Humans,
pubmed-meshheading:15168811-Incidence,
pubmed-meshheading:15168811-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15168811-Italy,
pubmed-meshheading:15168811-Male,
pubmed-meshheading:15168811-Middle Aged,
pubmed-meshheading:15168811-Mutation,
pubmed-meshheading:15168811-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:15168811-Odds Ratio,
pubmed-meshheading:15168811-Polymorphism, Genetic,
pubmed-meshheading:15168811-Probability,
pubmed-meshheading:15168811-Reference Values,
pubmed-meshheading:15168811-Risk Assessment,
pubmed-meshheading:15168811-Sex Distribution,
pubmed-meshheading:15168811-Statistics, Nonparametric
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pubmed:year |
2004
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pubmed:articleTitle |
CARD15 mutation analysis in an Italian population: Leu1007fsinsC but neither Arg702Trp nor Gly908Arg mutations are associated with Crohn's disease.
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pubmed:affiliation |
Cattedra di Gastroenterologia, Centro d'eccellenza per lo studio del rischio genomico in patologie complesse e multifattoriali, Università Tor Vergata, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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