rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2004-5-28
|
pubmed:abstractText |
Cyclooxygenase 2 (COX-2) is a target of aspirin and other non-steroidal anti-inflammatory drugs and is implicated in the pathogenesis of colorectal cancer. The objective of this study was to evaluate the extent of COX-2 in pre-malignant colorectal polyps and to assess the relationship between COX-2 and the level of dysplasia in these lesions.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0954-691X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
619-25
|
pubmed:dateRevised |
2009-10-16
|
pubmed:meshHeading |
pubmed-meshheading:15167166-Adenoma,
pubmed-meshheading:15167166-Adult,
pubmed-meshheading:15167166-Aged,
pubmed-meshheading:15167166-Aged, 80 and over,
pubmed-meshheading:15167166-Cell Transformation, Neoplastic,
pubmed-meshheading:15167166-Colon,
pubmed-meshheading:15167166-Colorectal Neoplasms,
pubmed-meshheading:15167166-Cyclooxygenase 2,
pubmed-meshheading:15167166-Disease Progression,
pubmed-meshheading:15167166-Female,
pubmed-meshheading:15167166-Humans,
pubmed-meshheading:15167166-Hyperplasia,
pubmed-meshheading:15167166-Immunoenzyme Techniques,
pubmed-meshheading:15167166-Isoenzymes,
pubmed-meshheading:15167166-Male,
pubmed-meshheading:15167166-Membrane Proteins,
pubmed-meshheading:15167166-Middle Aged,
pubmed-meshheading:15167166-Precancerous Conditions,
pubmed-meshheading:15167166-Prostaglandin-Endoperoxide Synthases
|
pubmed:year |
2004
|
pubmed:articleTitle |
The relationship between cyclooxygenase-2 expression and characteristics of malignant transformation in human colorectal adenomas.
|
pubmed:affiliation |
Department of Pathology, Epidemiology and Clinical Pharmacology, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland. katherinesheehan@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|