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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-5-28
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pubmed:abstractText |
Apolipoprotein (apo)CIII and apoAV play an important role in triglyceride metabolism as evidenced by the unambiguous and opposing phenotypes of transgenic and knockout mouse models. In this review we discuss studies on the genetics, protein structure, and regulation of apoCIII and apoAV and compare their potential molecular mechanisms of action in triglyceride metabolism. We examine the hypothesis that apoCIII and apoAV synergistically affect triglyceride metabolism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0957-9672
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-46
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15166778-Animals,
pubmed-meshheading:15166778-Apolipoprotein C-III,
pubmed-meshheading:15166778-Apolipoproteins,
pubmed-meshheading:15166778-Apolipoproteins A,
pubmed-meshheading:15166778-Apolipoproteins C,
pubmed-meshheading:15166778-Gene Expression Regulation,
pubmed-meshheading:15166778-Genetic Linkage,
pubmed-meshheading:15166778-Humans,
pubmed-meshheading:15166778-Hypertriglyceridemia,
pubmed-meshheading:15166778-Mice,
pubmed-meshheading:15166778-Mutation,
pubmed-meshheading:15166778-Triglycerides
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pubmed:year |
2004
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pubmed:articleTitle |
The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism?
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pubmed:affiliation |
Department of Human Genetics, Leiden University Medical Center, PO Box 9503, 2000 RA Leiden, The Netherlands. kowvd@lumc.nl
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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