|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2004-5-28
|
|
pubmed:abstractText |
Bioassay-guided purification of a methanol extract from Amomum tsao-ko led to the isolation of the bicyclic nonane isotsaokoin (1) as the major active principle, an isomer of the previously reported tsaokoin (2). The stereochemical relationship of 1 and 2 was investigated by NOE experiments and Mosher ester derivatization. Compound 1 showed antifungal activity against Trycophyton mentagrophytes.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0163-3864
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
67
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
889-91
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:15165158-Amomum,
pubmed-meshheading:15165158-Antifungal Agents,
pubmed-meshheading:15165158-Bicyclo Compounds,
pubmed-meshheading:15165158-Borohydrides,
pubmed-meshheading:15165158-Korea,
pubmed-meshheading:15165158-Molecular Structure,
pubmed-meshheading:15165158-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:15165158-Oxidation-Reduction,
pubmed-meshheading:15165158-Plants, Medicinal,
pubmed-meshheading:15165158-Stereoisomerism,
pubmed-meshheading:15165158-Trichophyton
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Isotsaokoin, an antifungal agent from Amomum tsao-ko.
|
|
pubmed:affiliation |
Department of Chemistry, Kongju National University, Kongju 314-701, South Korea. ssmoon@kongju.ac.kr
|
|
pubmed:publicationType |
Journal Article
|
