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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1992-10-8
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pubmed:abstractText |
The efficacy of cefetamet pivoxil (20 mg/kg and 10 mg/kg b.i.d.) was investigated in an open, prospective, randomized, comparative multicenter trial involving 148 children suffering from group A beta-hemolytic streptococcal (GABHS) pharyngo-tonsillitis. Phenoxymethylpenicillin given for 10 days was used as the reference drug and resulted in 15% treatment failures. After treatment with cefetamet pivoxil 20 mg/kg b.i.d., 2 failures (5.8%) were observed in 34 patients treated for 7 days and 2 (6%) in 33 patients after 10 days treatment. In 8 children treated with cefetamet pivoxil 10 mg/kg b.i.d. for 10 days, 7 were cured and 1 relapsed in the late follow-up. Recruitment for this dosage group is being continued. No serious adverse events occurred. Cefetamet pivoxil, given b.i.d., can be considered an alternative to phenoxymethylpenicillin in the treatment of GABHS pharyngo-tonsillitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0009-3157
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-7
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:1516463-Acute Disease,
pubmed-meshheading:1516463-Adolescent,
pubmed-meshheading:1516463-Ceftizoxime,
pubmed-meshheading:1516463-Child,
pubmed-meshheading:1516463-Child, Preschool,
pubmed-meshheading:1516463-Follow-Up Studies,
pubmed-meshheading:1516463-Humans,
pubmed-meshheading:1516463-Infant,
pubmed-meshheading:1516463-Penicillin V,
pubmed-meshheading:1516463-Pharyngitis,
pubmed-meshheading:1516463-Prospective Studies,
pubmed-meshheading:1516463-Streptococcal Infections,
pubmed-meshheading:1516463-Streptococcus pyogenes,
pubmed-meshheading:1516463-Tonsillitis
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pubmed:year |
1992
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pubmed:articleTitle |
Comparative study of cefetamet pivoxil and penicillin V in the treatment of group A beta-hemolytic streptococcal pharyngitis.
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pubmed:affiliation |
Department of Pediatrics, Free University of Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
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