rdf:type |
|
lifeskim:mentions |
umls-concept:C0003591,
umls-concept:C0011860,
umls-concept:C0023820,
umls-concept:C0023821,
umls-concept:C0032105,
umls-concept:C0035647,
umls-concept:C0041004,
umls-concept:C0052191,
umls-concept:C0286651,
umls-concept:C0441712,
umls-concept:C0441994,
umls-concept:C0547047
|
pubmed:issue |
6
|
pubmed:dateCreated |
2004-5-26
|
pubmed:abstractText |
Apolipoprotein (apo)C-III is a constituent of HDL (HDL apoC-III) and of apoB-containing lipoproteins (LpB:C-III). It slows the clearance of triglyceride-rich lipoproteins (TRLs) by inhibition of the activity of the enzyme lipoprotein lipase (LPL) and by interference with lipoprotein binding to cell-surface receptors. Elevated plasma LpB:C-III is an independent risk factor for cardiovascular disease. We studied the effect of atorvastatin on plasma LpB:C-III and HDL apoC-III.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0149-5992
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1358-64
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15161788-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15161788-Apolipoprotein C-III,
pubmed-meshheading:15161788-Apolipoproteins B,
pubmed-meshheading:15161788-Apolipoproteins C,
pubmed-meshheading:15161788-Diabetes Mellitus, Type 2,
pubmed-meshheading:15161788-Double-Blind Method,
pubmed-meshheading:15161788-Female,
pubmed-meshheading:15161788-Heptanoic Acids,
pubmed-meshheading:15161788-Humans,
pubmed-meshheading:15161788-Hypertriglyceridemia,
pubmed-meshheading:15161788-Lipoproteins, HDL,
pubmed-meshheading:15161788-Male,
pubmed-meshheading:15161788-Middle Aged,
pubmed-meshheading:15161788-Pyrroles,
pubmed-meshheading:15161788-Triglycerides
|
pubmed:year |
2004
|
pubmed:articleTitle |
Atorvastatin decreases apolipoprotein C-III in apolipoprotein B-containing lipoprotein and HDL in type 2 diabetes: a potential mechanism to lower plasma triglycerides.
|
pubmed:affiliation |
Department of Internal Medicine, University Medical Center Utrecht, Utrecht, the Netherlands. g.dallinga@erasmusmc.nl
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|