Source:http://linkedlifedata.com/resource/pubmed/id/15161784
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2004-5-26
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pubmed:abstractText |
ACE inhibitor therapy is widely used in lower-risk patients with type 2 diabetes to reduce mortality, despite limited evidence to support this clinical strategy. The aim of this study was to evaluate the association between ACE inhibitor use and mortality in patients with diabetes and no cardiovascular disease. RESEARCH DESIGN AND SETTINGS: Using the Saskatchewan health databases, 12,272 new users of oral hypoglycemic agents were identified between the years of 1991 and 1996. We excluded 3,202 subjects with previous cardiovascular disease. Of the remaining subjects, 1,187 "new users" of ACE inhibitors were identified (ACE inhibitor cohort). Subjects not receiving ACE inhibitor therapy throughout the follow-up period served as the control cohort (n = 4,989). Subjects were prospectively followed until death or the end of 1999. Multivariate Cox proportional hazards models were used to assess differences in all-cause and cardiovascular-related mortality between cohort groups.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0149-5992
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1330-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15161784-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15161784-Cardiovascular Diseases,
pubmed-meshheading:15161784-Databases, Factual,
pubmed-meshheading:15161784-Diabetes Mellitus, Type 2,
pubmed-meshheading:15161784-Diabetic Angiopathies,
pubmed-meshheading:15161784-Female,
pubmed-meshheading:15161784-Humans,
pubmed-meshheading:15161784-Male,
pubmed-meshheading:15161784-Middle Aged,
pubmed-meshheading:15161784-Proportional Hazards Models,
pubmed-meshheading:15161784-Reproducibility of Results,
pubmed-meshheading:15161784-Retrospective Studies,
pubmed-meshheading:15161784-Treatment Outcome
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pubmed:year |
2004
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pubmed:articleTitle |
Reduced mortality associated with the use of ACE inhibitors in patients with type 2 diabetes.
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pubmed:affiliation |
Institute of Health Economics #1200, 10405 Jasper Ave., Edmonton, Alberta, Canada T5J 3N4.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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